Overall, the study sheds new light on how environmental factors, such as viral or bacterial infections, poor diet, pollution or other hazardous exposures, can interact with the human genetic blueprint and have disease-influencing consequences. The study shows that a protein produced by the Epstein-Barr virus, called EBNA2, binds to multiple locations along the human genome that are associated with these seven diseases.
Critical contributions were provided by Xiaoting Chen, PhD, and Mario Pujato, PhD, both also in CAGE. The project was led by three scientists: John Harley, MD, PhD, Director of the Center for Autoimmune Genomics and Etiology (CAGE) at Cincinnati Children’s and a faculty member of the Cincinnati VA Medical Center Leah Kottyan, PhD, an immunobiology expert with CAGE and Matthew Weirauch, PhD, a computational biologist with the center. Study results were published today in the journal Nature Genetics. Combined, these seven diseases affect nearly 8 million people in the U.S. Those diseases are: systemic lupus erythematosus (SLE), multiple sclerosis (MS), rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), inflammatory bowel disease (IBD), celiac disease, and type 1 diabetes. QUESTION Bowel regularity means a bowel movement every day.A far-reaching study conducted by scientists at Cincinnati Children’s reports that the Epstein-Barr virus (EBV)-best known for causing mononucleosis-also increases the risks for some people of developing seven other major diseases. Mono may cause the spleen to become enlarged and strenuous activities such as sports may cause the spleen to rupture.Avoid contact sports until you fully recover.Acetaminophen and ibuprofen may be used in children, but aspirin should not be given to young children with mono because of possible liver complications.Over-the-counter (OTC) medications for pain and fever.Home remedies to relieve symptoms of mono in adults may include: The goal of treatment for mono is the relief of symptoms.
There are currently no antiviral medications that are effective to treat or cure Epstein-Barr virus. Mono is caused by a virus, so antibiotics are not used to treat it. Rarely, symptoms of mono last six months or more. Some people may continue to feel fatigue for several more weeks. Mono (infectious mononucleosis) in adults is generally not considered a serious illness and most people recover completely within one to four weeks without any complications. What Is the Treatment for Mono in Adults? Older adults with mono often do not have the same symptoms as children and younger adults such as swollen lymph nodes, sore throat, enlarged spleen, or increased white blood cells.
Symptoms of mono in adults may come on slowly and usually develop four to eight weeks after infection. Commonly called “the kissing disease,” mono often affects adolescents and young adults. “ Mono” ( infectious mononucleosis) is a contagious infection that can cause fever, sore throat, fatigue, and enlarged lymph nodes in the neck. Symptoms of mono that are more common in older adults include fever (temperature greater than 100.4☏ or 38☌), swollen liver, and body aches.
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